Weirder Diseases

Pneumonia, syphilis, mummy rot or the plague are nice and all, but maybe you want some stranger diseases for a change?

d30 Diseases

1. Asonia: You negate sounds. Not only you cannot speak, but you walk, fight or scream in complete silence. You also cannot hear, as the sounds don't reach your inner ear.
   
2. Astral hiccups: Any time you are scared or surprised, you experience an involuntary, uncontrolled teleporation.
3. Biokinetic drift: Your body is not yours. Every day, Save or reroll your race and sex.
4. Bone blight: Bone protrusions pierce your skin from the inside. Loose 1 maximum hp per day, but gain a passive counterattack dealing 1d6 damage from the spikes. Even if the disease is cured, the spikes and hp loss do not go away. Try a biomancer to fix that.
5. Chronal tumour: Whenever you go to sleep, Save or fall into future. First days, then weeks, months or years.
6. Clockwork virus: Loud ticking is heard from your innards instead of heartbeat. Loose 1d4 Constitution and Intelligence per day as you turn into a clockwork automaton. Once you reach 0, there is nothing but your skin left over the cogs, axles and pulleys.
7. Common fire: Where common cold is caused by cold and wet, common fire is caught in hot and dry places. Loose 1d4 Strength per day and cough up smoke.
8. Cooties: You can only infect and be infected by members of the other sex. Loose 1d6 Charisma per day. You become more and more nervous, awkward and incompetent around the other sex.
9. Eyeball cancer: You grow new eyeballs all over your body. One by one, they will detach as floating eyes and fly away. That's how floating eyes reproduce.
10. Enflamed eyes: Anything you leave your eyes on for more than a few seconds will burst into flames.
11. Hecatoncheiritis: Grow one new, fully functional arm per month. Becomes a real problem once you have so many arms you can barely move.
12. Hollowing: You feel empty inside. Your thoughts are slower, emotions dull. Nothing scares or excites you. Loose 1d6 Wisdom per day. Once you reach 0, any damage crumbles you into a pile of grey ash, revealing you were actually hollow inside.
13. Hyperfertility: All of your bodily fluids cause impregnation on skin contact, even in males with 5% chance. If you're female, you can impregnate other females but cannot be self-impregnated.
14. Hypergravity syndrome: Your personal gravity field slowly collapses. It will become harder and harder to move as you weight twice, thrice, five times more than normal. Loose 1d6 Strength per day. Most people are cured or die before they can form a miniature black hole.
15. Lucky death: Four-leaf clover lesions cover your body. You may reroll any roll except Saves against this disease at the cost of 1d6 points from random attribute. If you don't use this ability at least once per day, loose 1 point from every attribute.
16. Magicbane: A spell has died in your brain and now other magic is avoiding its carcass. Effectively you have an antimagic field extending 5' around your body. Don't forget that even things like potions, portals or enchanted prosthetics are suppressed.
17. Massmind malaise: You feel strangely stretched out. Loose 1d6 Intelligence per day and broadcast your every emotion and thought to creatures within 30'.
18. Mortambulism: Your body forgot how to die. You remain aware no matter your injuries, but once damaged beyond your natural healing ability, you cannot be easily put together again. Enjoy eternity in pieces.
19. Phase fever: You flicker in and out of this dimension. Every physical interaction has a chance to fail as you turn intangible at the wrong moment. The chance starts at 1-in-6 and grows as the illness progresses.
20. Phytogenetic disorder: You turn somewhat green. Loose 1d6 Strength every day unless you had at least four hours of sunlight.
21. Psionic self-loathing: Add an evil twin of yourself to the random encounter table. It's a tulpa that you unconsciously create, bent on destroying you and all that you value. Even if killed, it will return again and again until this disease is cured.
22. Psychic seizures: Your soul leaks from your body. Loose 1d4 Intelligence and Wisdom per day. Every time you take damage, all creatures within 10' must Save vs stun as you broadcast the pain.
23. Regressive crystallization: Loose 1d3 Dexterity and Constitution per day as you slowly turn brittle and crystalline. At least you'll leave behind a beautiful statue.
24. Rockefeller's disease: Loose 1d4 Constitution per day. A number of sores on your body steadily seeps with black, highly flammable puss.
25. Rust plague: Your sweat and tears are flakes of rust. Your touch causes rapid rusting. Loose 1d3 Dexterity and Charisma per day.
26. Spontaneous combustion syndrome: This disease lays dormant until the time of death. Then you explode, dealing 3d6 fire damage in 10' radius and infecting everyone burnt with the disease.
27. The drips: Your nose drips with green slime. You are immune to its effects, but your equipment and allies not so much.
28. The shivers: You are bluish in complexion and so cold you are covered in rime. Unless constantly warmed up, you will freeze to death. Loose 1d6 Dexterity and Constitution per day.
29. Throat rot: Your throat is sore and your tongue is covered in putrescent blisters. Loose 1d4 Constitution per day, plus Save or vomit every time you try to eat. If you fail three daily Saves in a row, your tongue rots off completely.
30. Unlight sickness: Light no longer interacts right with your diseased body. You are invisible in direct light and translucent in dim light. Loose 1d4 Charisma per day.